Significant pathway and biomarker identification of pancreatic cancer associated lung cancer

Pancreatic Cancer (PC) is the seventh leading cause of cancer-related death worldwide and one deadliest malignant neoplasms. It difficult to diagnose at an early stage. Lung (LC) second most common cancer a tumor which spreads into nearby tissues through metastasis. One major risk factors between PC LC smoking. Since both are they may be associated with another. The main purpose this research was find genetic linkage association bioinformatics approach. We analyzed gene expression datasets compared significant markers shared genes two cancers. identified 1686 LC, 33.2% datasets. enrichment analysis disclosed biological roles selected revealed pathways that were mostly biomarkers. Using cancers we constructed PPI network 10 hub (TP53, AKT1, EGFR, TNF, IL6, ALB, EGF, MYC, VEGFA, GAPDH) based on their connectivity degree values. In drug target analysis, compound ‘Capsaicin CTD 00005570’ all genes. This could useful for treatment patient who suffers simultaneously from Thus study elemental functional help in development future medications patients LC.